Silvaris Cancer Institute — San Diego, CA

SilverOak Cancer Institute San Diego is a 220-bed dedicated cancer hospital where every physician, nurse, researcher, and support professional works toward a single mission: defeating cancer through the most scientifically advanced, compassionate, and personalized care available. Located in one of the world's great centers of biomedical research, SilverOak San Diego maintains a formal research collaboration with UCSD's Moores Cancer Center and the Salk Institute for Biological Studies, creating a pipeline from laboratory discovery to clinical application that benefits patients today and tomorrow.

Clinical trials are the engine of SilverOak Cancer Institute San Diego. Our investigational therapeutics portfolio encompasses more than 70 active clinical trials at any given time, spanning Phase I first-in-human studies of novel targeted agents to Phase III practice-defining comparative effectiveness trials. Our patient-to-trial matching team — comprising a dedicated trials navigator, data manager, and protocol nurse — evaluates every new patient for trial eligibility, ensuring that the opportunity to access investigational therapy is offered proactively rather than as an afterthought.

CAR-T cell therapy, an area where SilverOak San Diego holds particular expertise, is offered for FDA-approved indications in large B-cell lymphoma, multiple myeloma, follicular lymphoma, and mantle cell lymphoma, with an active clinical trials program exploring CAR-T in solid tumors. Our melanoma center draws patients from across Southern California, Baja California, and the broader Pacific Southwest for management of early-stage, locally advanced, and metastatic melanoma using the latest combination immunotherapy regimens and targeted BRAF/MEK inhibition. Breast oncology is a further area of specialization, with a Comprehensive Breast Cancer Program offering molecular subtyping, germline and somatic genomic testing, and enrollment in multiple active clinical trials.

SilverOak Cancer Institute San Diego believes that survivorship is as important as active treatment. Our survivorship program provides structured follow-up surveillance, management of therapy-related long-term toxicities, fertility preservation consultation before treatment begins, and a robust peer support program that connects newly diagnosed patients with trained survivor mentors who have lived through the same diagnosis. San Diego's exceptional outdoor environment is leveraged therapeutically through our oncology wellness program, offering beach-side yoga, hiking groups, and nutritional cooking classes that reinforce recovery and quality of life well beyond the clinic walls.